Preparation and Evaluation of Nifedipine sustained release Tablet by using Natural Gums as release retardant

Formulation and Evaluation of Sustained Release Metoprolol Succinate Tablet using Hydrophilic gums as Release modifiers

The objective of this study was to design and evaluate oral sustained drug delivery system for Metoprolol succinate using natural hydrophilic gums such as karaya gum and xanthan gum as a release modifier. Nine batches were prepared by using karaya gum (KG) and xanthan gum (XG) in concentration of 15%, 20% and 25% alone and in combination of 2:8. Matrix tablets were prepared by wet granulation m...

Formulation and Evaluation of Sustained Release Tablets Using Prunus armeniaca (L.) and Prunus domestica (L.) Gums

Preparation and Evaluation of Sustained Release Matrix Tablet of Diclofenac Sodium using Natural Polymer

Sustained release tablets of Diclofenac Sodium were fabricated using Cashew nut tree gum, HPMC and Carbopol . The tablets were evaluated for preformulation studies like angle of repose, bluk density, compressibility index and physical characteristics like hardness, weight variation, fraibilty and drug content. In-vitro release of drug was performed in PBS pH 7.2 for twelve hours. All the physic...

Formulation and In Vitro Evaluation of Extended Release Tablets of Paliperidone Using Natural Gums

Paliperidone is a well known dopamine antagonist of the atypical antipsychotic class. In the present study Paliperidone was formulated as ER release tablets using natural and synthetic polymers separately or in combination. The aim of ER release formulation is to reduce the frequency of dosing. Tablets are prepared by direct compression method. The optimized formulations contain Paliperidone as...

Preparation and release study of Levetiracetam 500 mg extended release tablet by using combination of hydrophilic and hydrophobic polymers.

Abstract Levetiracetam as an Anti-epileptic drug with exclusive mechanism of action is accepted by the USA Food and Drug Administration as an adjunctive therapy in treating epilepsy in young adults. The purpose of this project is the design and formulation of prolonged release of levetiracetam using two types of retarding agent such as Hydroxyl Propyl Methylcellulose (HPMC K4...